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Office No. 106, 1st Floor,
Jumeirah Lake Towers, Cluster X,
Jumeirah Bay X3, Sheik Zayed Road, Dubai, UAE

+971 4 578 7232
P.O.Box: 338334

info@scipharm.ae

Com.Pl.it DX® Liquid

Com.Pl.it DX® Liquid

The Com.Pl.it DX® Liquid test can be conducted before to selecting a treatment and for tumor surveillance throughout therapy. It also aids in identifying secondary mutations, which may necessitate adjustments to the treatment regimen.

Selecting a Suitable Treatment Strategy for Each Solid Tumor:

Com.Pl.it DX® Liquid is intended for all solid tumors and offers real-time insights into the tumor’s genetic profile through the non-invasive technique of liquid biopsy.

The Com.Pl.it DX® Liquid multigene liquid biopsy test is primarily indicated for:

  • Patients with inoperable neoplasms and those with insufficient or inadequate tissue samples.
  • Individuals having numerous metastases.
  • Patients receiving treatment or post-treatment.

Patients receiving treatment or post-treatment.

-The Com.Pl.it DX® Liquid biopsy test aids in formulating a treatment strategy.
-It ascertains the molecular profile (gene mutations) of the tumor and the relationships among genes in instances of numerous mutations.
-Identifies on-label medications, if relevant, that target either the mutant genes or the associated pathways.
-Identifies variants linked to resistance against targeted medicines.

Identifies off-label therapies or interventions in clinical trials informed by tumor genetic profiling. This may be especially significant for those for whom conventional treatment has been ineffective.

Genetic Panel

64 Genetic Mutations

Gene 1Gene 2Gene 3Gene 4Gene 5
AKT1ALKAPCARAFATM*
BRAFBRCA2*CDH1CDKN2A*CSF1R
CTNNB1DDR2EGFR*ERBB2*ERBB3
ERBB4EZH2FBXW7FGFR1FGFR2*
FGFR3*FLT3FOXL2GNA11GNAQ
GNASHNF1AHRASIDH1IDH2
JAK2KDRKEAP1KITKRAS*
MAP2K1MDM2MET*MLH1*MYC
NOTCH1NPM1NRASNTRK1NTRK2
NTRK3PDGFRAPIK3CA*POLEPTEN*
PTPN11RAF1RB1*RETROS1
SMAD4SMARCA4SMARCB1SMOSPOP
STK11TERTTP53*VHL* 

9 Gene Rearrangements

ALK, ROS1, RET, FGFR1, FGFR2, FGFR3,
NTRK1, NTRK2, NTRK3

64 Genes with SNV/Indels Analyzed
AKT1 ALK APC ARAF ATM* BRAF BRCA2* CDH1
CTNNB1 DDR2 EGFR* ERBB2* ERBB3 ERBB4 EZH2 FBXW7
FGFR3* FLT3 FOXL2 GNA11 GNAQ GNAS HNF1A HRAS
JAK2 KDR KEAP1 KIT KRAS* MAP2K1 MDM2 MET*
NOTCH1 NPM1 NRAS NTRK1 NTRK2 NTRK3 PDGFRA PIK3CA*
PTPN11 RAF1 RB1* RET ROS1 SMAD4 SMARCA4 SMARCB1
STK11 TERT TP53* VHL* SMO SPOP POLE PTEN*
IDH1 IDH2 MYC MLH1* CDKN2A* CSF1R FGFR1 FGFR2*

Fusions

ALK FGFR1 FGFR2 FGFR3 NTRK1 NTRK2 NTRK3 RET ROS1

MSI

15 loci

 To conduct the Com.Pl.it DX® Liquid biopsy multi-gene test, a minimal quantity of blood from the patient is required in a specialized Streck™ vial, supplied by Scipharm.

Exemplary Outcomes Report

Common Inquiries

It encompasses all varieties of solid tumors, including those of indeterminate origin.

Blood in a specialized STRECK vial provided by Scipharm. Blood in a specialized collection vial that you will retrieve from Scipharm. Cell-Free DNA BCT® (10 ml) and Cell-Free RNA BCT® (10 ml).

Scipharm is tasked with the provision and distribution of the specialized vial for the Com.Pl.i.t DX® Liquid test. Kindly reach out to us.

Scipharm is accountable for all requisite procedures concerning the receipt and return of your sample

Your results will be transmitted to your physician through a secure network and to you via email, accompanied by a secure unique code issued by customer service.

Results will be accessible within 15 business days following the receipt of your sample.

The Customer Service Department will issue a distinct e-banking payment code, or payment may be executed bank transfer.

Compliance with data protection regulations is also necessary.

Our Customer Service Team is dedicated to addressing your inquiries concerning the services provided by Scipharm. For inquiries regarding the ordering of tests, please contact us directly.

To finalize the test, you must complete and submit the Consent form available at the link below.

Download Consent form